Pharm
Dapsone is structurally related to the sulphonamides.
It is bacteriostatic for M. leprae, and resistant strains may be encountered.
Dapsone also is used in the treatment of pneumonia caused by Pneumocystis jiroveciiin immunosuppressed patients.
Adverse reactions include hemolysis(especially in patients with glucose-6-phosphate dehydrogenase deficiency), methemoglobinemia, and peripheral neuropathy.
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